With ProLon, you are biologically fasting for 5 consecutive days while consuming food.

The purpose of mimicking and enhancing a 5-day fasting state is to induce the body’s natural protective & regenerative capabilities; FMDs have been proven by the Longevity Institute at the University of Southern California (USC) to clinically induce multiple healthy systemic, metabolic and cellular effects.1,2

Based on the identification of the genes and pathways that regulate aging and cellular protection, ProLon promotes regenerative and rejuvenative changes, including effects on a wide range of markers that contribute to aging, such as cholesterol, inflammation, and fasting glucose. It has been clinically tested and found to promote beneficial effects in a variety of conditions ranging from excess weight to growth factors associated with DNA damage.

ProLon contains 66 unique ingredients that have been studied for over a decade at USC, under the sponsorship of the NIH, to inactivate nutrient sensing pathways while providing nourishment for the body (macronutrients, micronutrients, minerals and vitamins) as well as mimicking and enhancing a fasting state. ProLon is plant-based and comes in a compact box which contains 5 smaller boxes (one for each day). A typical day box contains a variety of bars, soups, snacks, drinks, and supplements. Day 1 is 1100 calories while each of the other 4 days are around 770 calories. While total calories are one dimension of the product, the most important dimension is the proprietary and patented formulation that mimics and enhances a fasting state. Additionally, ProLon is Gluten and Dairy Free.

The body identifies the presence of food through nutrient-sensing pathways:

  • IGF-1, MTOR (Mechanistic Target of Rapamycin), and PKA (Protein Kinase A) are 3 key nutrient-sensing pathways that recognize the presence of protein, carbohydrates (sugars)
  • These nutrient-sensing pathways are pro-growth and pro-aging, and lead to many common health problems including heart disease and cancer
  • ProLon down-regulates these pathways, enhancing a fasting mode and activating cellular regeneration and rejuvenation

* ProLon allows you to eat while tricking your body into acting like it’s fasting *


ProLon® meals come in 5 small boxes (one for each day) that include plant-based energy bars, soups, a variety of snacks, drinks, and supplements. All are carefully studied and designed to nourish your body and promote positive changes in metabolic markers, cellular rejuvenation, reduced inflammation, and healthy aging.


ProLon ingredients are plant-based and do not contain any additives, preservatives* or chemicals. The daily caloric intake with ProLon is between 770 and 1100 calories from healthy ingredients that maximize nourishment and provide a pleasant eating experience.
*ProLon energy drink contains the natural preservative polylysine.


ProLon market research and consumer panels demonstrated:
  • Very good taste
  • Convenient single-day packaging
  • Minimal disruption to daily lifestyle